Having a chance to choose where to stay, definitely my suggestion goes to a luxury room in Margutta street. Full of charme and quietness, even when extremely central, via Margutta is the street of painters. some general info for you:
http://en.m.wikipedia.org/wiki/Via_Margutta
http://www.romasegreta.it/campo-marzio/via-margutta.html

There is one culinary reason for visiting via Margutta from via del Babuino: a great vegetarian restaurant: il Margutta. I had a chance to spend a Saturday’s brunch with a couple of old friends. Experience was special and to be made again, without doubt. We have been perfectly welcomed by a professional staff, young and discrete. to wait for us a beautiful room, with a pianist playing ambient music. art everywhere in the wall, to remind the importance of the street for galleries and art workshops. a buffet “a discretion” for 25 euro, including dessert, water and wine. we spent couple of hours enjoying food, drinks in a refined athmosphere, without being pretentious.